IL-18 Receptor Complex: Potential Drug & Biomarker Targets (P42105)

Target Name: Interleukin-18 Receptor Complex

NCBI ID: P42105

Other Name(s): IL-18 Receptor complex | IL-18R

IL-18 Receptor Complex: Potential Drug & Biomarker Targets

The Interleukin-18 Receptor Complex (IL-18 Receptor complex) is a protein complex that plays a crucial role in the regulation of immune and inflammatory responses.IL-18 Receptor complex is composed of several proteins including IL-18 receptor alpha chain (IL -18RA), IL-18 receptor beta chain (IL-18RB), and IL-18 receptor gamma chain (IL-18RG). The IL-18RA and IL-18RB proteins are involved in the intracellular signaling cascade, while IL-18RG is involved in the in vitro signaling.

The IL-18 Receptor complex is involved in the regulation of various immune and inflammatory responses, including inflammation, pain, and survival. The IL-18 Receptor complex is also involved in the regulation of cell survival, angiogenesis, and inflammation.

IL-18 Receptor complex is a potential drug target in the treatment of various diseases, including cancer, autoimmune diseases, and chronic obstructive pulmonary disease (COPD).

Drugs that target the IL-18 Receptor complex have been shown to have efficacy in treating various diseases, including cancer, autoimmune diseases, and COPD. For example, a drug called ALZ-801 is currently being investigated for its potential to treat cancer by targeting the IL-18 Receptor complex.

In addition to its potential as a drug target, the IL-18 Receptor complex is also a potential biomarker for various diseases. The IL-18RA and IL-18RB proteins are involved in the intracellular signaling cascade, which makes them potential indicators of inflammation and inflammation immune responses. Therefore, measuring the levels of these proteins can be used as a biomarker for various diseases, including cancer, autoimmune diseases, and COPD.

In conclusion, the IL-18 Receptor complex is a protein complex that plays a crucial role in the regulation of immune and inflammatory responses. It is a potential drug target and biomarker for various diseases, including cancer, autoimmune diseases, and COPD. Further research is needed to fully understand the role of the IL-18 Receptor complex in the regulation of immune and inflammatory responses and its potential as a drug and biomarker.

Protein Name: Interleukin-18 Receptor Complex

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